Nicotinamide Riboside Malate

Shaanxi Rebecca Biotechnology Co., Ltd. is a professional manufacturer integrating R&D, standardized production and global supply service of high-purity nutritional ingredients. Our production workshops strictly follow cGMP and ISO22000 management systems, ensuring every batch of products meets international food-grade safety standards.

We adopt advanced enzymatic biosynthesis technology, matched with multi-stage membrane filtration and vacuum crystallization systems to produce pure and low-residue ingredients. The whole production process abandons harmful chemical catalysts, completely avoiding residual impurities. Our in-house laboratory is equipped with HPLC, ICP-MS and GC-MS precision testing equipment to conduct full-index batch inspection on product purity, heavy metals, microorganisms and solvent residues.

All our products comply with EU EC396, EU 2023/915, ICH Q3C and FDA GRAS specifications. We provide complete certification documents including COA and MSDS, as well as Halal and Kosher certificates to support smooth global customs clearance. We offer flexible customization services covering product purity, formula adjustment and personalized packaging, fully adapting to differentiated market demands. With stable inventory and temperature-controlled global logistics, we can support both small-batch trial orders and large-scale commercial procurement of Nicotinamide Riboside Malate.

We adopt green enzymatic biosynthesis technology to produce high-quality raw materials, different from traditional chemical synthesis processes. The whole production uses food-grade biological substrates, without adding toxic reagents and heavy metal catalysts, ensuring high safety and pure product properties.

All raw material suppliers are strictly screened and qualified, with complete supplier qualification files and batch traceability records. We establish a full-chain quality tracking system from raw material incoming inspection, production processing to finished product delivery. Every batch of Nicotinamide Riboside Malate can be traced back to the raw material source and production parameters, fully meeting the strict safety supervision requirements of Europe, America and other mainstream markets.

This ingredient features excellent water solubility, which can dissolve quickly to form clear and transparent solutions, suitable for liquid drinks, solid beverages and various oral formula products. It also has good solubility in methanol and ethanol, while it is insoluble in oil-based systems, making it exclusive for water-based nutritional formulations.

For stability performance, the sealed powder maintains complete biological activity for 24 months under low temperature (2–8°C), dark and dry storage conditions. The prepared aqueous solution is recommended for immediate use or refrigerated storage to prevent activity degradation. The product remains stable in weak acid to neutral pH environments (4.0–7.5), but it is prone to structural decomposition under strong alkaline conditions or high temperature above 60℃. Standard sealed and moisture-proof storage can effectively avoid hygroscopicity and activity loss.

We adopt standardized eight-step production procedures to ensure stable product quality and high purity throughout batches.

Firstly, high-purity food-grade substrates are precisely proportioned and activated as raw materials.

Professional synthetases are used for constant-temperature enzymatic catalysis under mild conditions to prepare crude nicotinamide riboside liquid.

Subsequently, malate complexation treatment is carried out to stabilize the molecular structure and improve human absorption and utilization rate.

Multi-stage filtration removes residual proteins and enzyme impurities, and vacuum concentration is applied to eliminate excess solvents.

Gradient crystallization technology is used for deep purification to upgrade the product to pharmaceutical-grade purity.

Finally, vacuum sterile drying and UV sterilization are completed, and finished products are packaged in a dust-free workshop.

Each production batch will undergo comprehensive quality verification and file recording before delivery, with strict quality control in every link.

Our quality management system covers the whole product life cycle from raw material procurement, in-process production to finished product delivery. We implement strict cGMP production specifications and real-time production monitoring mechanisms.

We adopt professional analytical technologies including HPLC purity detection, ICP-MS heavy metal screening and standardized microbial testing to control product quality. Every batch is equipped with complete traceability records and official COA documents. We also support authoritative third-party laboratory testing and validation according to customer demands. All safety indicators meet global food-grade standards, with total heavy metal content strictly controlled below 3ppm and microbial indicators within safe limits.

Our standard packaging adopts double-layer food-grade PE inner bags matched with fiber drums, with multiple specifications of 1kg, 5kg, 10kg and 25kg. This packaging design can effectively isolate moisture and light, preventing product damage and activity loss during transportation. For high-precision and ultra-sensitive orders, we provide nitrogen-filled aluminum foil bags for enhanced protection.

We support personalized customization services such as private label printing and customized packaging specifications to match customers’ brand positioning. We cooperate with top international logistics providers to offer air freight, sea freight and express delivery services, with professional temperature-controlled transportation to ensure product stability in long-distance transit.

Our professional export team sorts out complete customs clearance documents including COA, phytosanitary certificate and regulatory compliance files for each shipment, and provides real-time logistics tracking. The conventional delivery cycle is 7–15 working days, covering global mainstream markets.

Q1: What are the advantages of NR Malate over conventional NR Chloride?

A1: The malate-stabilized formula removes chloride ions, effectively avoiding gastrointestinal irritation. It features higher bioavailability and better tolerance, ideal for long-term anti-aging supplementation formulas.

Q2: How to choose between 98% and 99% purity grades?

A2: 98% purity is cost-effective for mass commercial formulations, while 99% high-purity grade is suitable for premium products, export markets and professional scientific research scenarios.

Q3: What is the correct way to store the product?

A3: Please store the sealed product at 2–8°C low temperature, away from light and moisture. It is recommended to use up the opened product within 3 months to maintain optimal biological activity.

Q4: Can this ingredient be compounded with other anti-aging raw materials?

A4: Yes, it has good compatibility. It can produce synergistic effects with resveratrol, CoQ10, pterostilbene and other ingredients without stability conflicts, suitable for multi-component compound formulas.

Q5: Can you provide third-party test reports?

A5: Sure. We can provide ISO 17025 accredited laboratory test reports including purity, heavy metals and microbial safety for each batch to support customer market audit and declaration.

If you have inquiries about Nicotinamide Riboside Malate technical parameters, formula matching, sample application and bulk order cooperation, please feel free to contact our professional team via information@sxrebecca.com. We provide professional customized ingredient solutions with pharmaceutical-grade quality to support your development of high-end anti-aging wellness products and global market expansion.