Formononetin Extract​

Shaanxi Rebecca Biotechnology Co., Ltd. integrates professional technical advantages and large-scale standardized production capacity to provide stable and high-quality plant extract raw materials. Our professional R&D team adopts low-temperature extraction and preparative chromatography technology to effectively protect the structural integrity of heat-sensitive isoflavones and avoid active ingredient degradation. Equipped with advanced HPLC and ICP-MS precision testing instruments, we conduct full-index quality inspection for every batch of products.

Our production workshop complies with cGMP, ISO9001 and HACCP system standards, flexibly meeting laboratory small-batch trial production and industrial ton-level bulk order demands. We can provide complete supporting documents such as COA, HPLC spectrum reports and MSDS, and support authoritative third-party testing verification. We offer diversified customized services covering product purity, particle size and batch specification, fully adapting to academic research and commercial supplement production needs, and our stable output capacity makes Formononetin Extract your cost-effective high-purity isoflavone raw material choice.

All red clover raw materials are sourced from standardized planting bases in northern China.

The local cool climate and sufficient sunlight create superior growth conditions, which effectively promote the synthesis and accumulation of isoflavone active ingredients.

All raw materials pass non-GMO certification and strict pre-production screening for heavy metals and pesticide residues, with only high-quality flowering tops rich in formononetin precursors selected for extraction processing.

We implement a complete batch traceability system, linking each finished product with planting origin, harvesting time, production parameters and test data to realize full supply chain transparency and controllability.

We support graded product supply, including pharmaceutical-grade high-purity products for clinical research and customized specification products for commercial formula production, ensuring every batch of Formononetin Extract delivers consistent and reliable quality.

Formononetin itself is slightly soluble in water, but it can be quickly dissolved in DMSO, methanol and ethanol solvents. For water-based formula products, microencapsulation technology or auxiliary solvents such as polysorbate-80 can be used to improve dispersion effect. The product maintains stable chemical properties below 60°C; long-term high-temperature environment will easily cause oxidative degradation and color change of active ingredients.

It shows excellent stability in acidic to neutral pH environments (pH 4–7), while strong alkaline conditions will destroy its molecular structure and cause efficacy attenuation. This ingredient is photosensitive and requires strict light-proof storage to avoid oxidation and potency loss caused by UV irradiation. In addition, the product has low hygroscopicity, but long-term exposure to humid air will affect powder fluidity and appearance. It is compatible with most neutral and weakly acidic plant raw materials, and it is recommended to avoid mixing with strong oxidants.

The whole production process starts with strict raw material inspection and impurity removal, with all raw materials tested to confirm no pesticide residue and heavy metal excess. The crushed red clover raw materials adopt ethanol-water circulating extraction at a low temperature below 55°C to maximize the retention of isoflavone active ingredients. After multi-stage filtration to remove plant debris and colloidal impurities, the extract is concentrated by vacuum low-temperature technology to recover solvents and obtain high-concentration stock solution.

We use macroporous resin chromatography to separate total isoflavones from sugars, pigments and other invalid impurities, and further adopt preparative HPLC technology to accurately separate formononetin from other isoflavone components such as biochanin A, genistein and daidzein. After nanofiltration desalting treatment, the product is recrystallized and refined to ensure the final purity reaches ≥98%. The whole drying process is controlled at ≤60°C with light-proof treatment to prevent thermal and photodegradation.

Finally, after precise crushing and sieving to uniform particle size, each batch of products will pass full-index tests including HPLC purity detection, ICP-MS heavy metal detection and microbial detection. Qualified products are packaged in dust-free workshops with double PE inner bags, aluminum foil vacuum bags and fiber drums to ensure stable product quality during storage and transportation.

We adopt a dual quality control mode of in-house testing plus optional third-party verification, covering all core indicators such as product appearance, HPLC purity, moisture content, ash content, heavy metals, microorganisms and pesticide residues. Each shipment is equipped with official COA, HPLC chromatogram and MSDS documents to support customer market declaration and audit work.

All production links strictly comply with USP monograph specifications and EU plant extract industry standards, and operate under the standardized management of ISO9001 quality system and ISO22000 food safety system. Eligible batches can provide Halal and Kosher certification services upon request, helping customers quickly open up global high-end markets.

Our standard bulk package is 25kg fiber drum, equipped with double food-grade PE inner bags and aluminum foil vacuum barrier layers, which can effectively isolate moisture and light and fully protect product activity during transportation. For laboratory research, sample testing and small-batch trial production, we provide 1kg and 5kg portable aluminum foil sealed packaging.

We support personalized customized services such as private label and special packaging specifications to meet customers’ brand packaging and product matching needs. We provide diversified logistics solutions including air freight, sea freight and express delivery, and support temperature-controlled transportation for sensitive ingredients. Flexible trade terms such as FOB, CIF and DDP are available to adapt to different international procurement modes. The conventional delivery cycle is 7–14 working days after order confirmation, with stable and efficient supply capacity.

Q1: What are the raw material sources of your product?

A1: It is extracted from non-GMO red clover flowering tops from northern China standardized planting bases, with all raw materials pre-screened for heavy metals and pesticide residues to meet EU safety standards.

Q2: What purity specifications can you provide?

A2: Our mainstream specification is ≥98% high-purity grade tested by HPLC. We can also customize special purity grades according to customers’ project and formulation requirements.

Q3: How to solve the poor water solubility of the product?

A3: Water solubility can be effectively improved by adding organic co-solvents or adopting microencapsulation technology, which is applicable for capsule, beverage and other aqueous formula products.

Q4: What storage conditions are required to guarantee shelf life?

A4: The product is sensitive to high temperature (over 60°C), strong alkali and ultraviolet light. Sealed, cool, dry and light-proof storage is required to maintain the 24-month valid shelf life.

Q5: What certification and test documents can be provided?

A5: We provide standard COA, HPLC chromatogram, MSDS and specification sheets. Halal, Kosher and factory audit documents are available upon customer request.

If you have any demands for Formononetin Extract technical consultation, sample application, customized specification adjustment and bulk order quotation, please feel free to contact our professional team via information@sxrebecca.com. We provide targeted product solution matching services according to your formula needs and regional regulatory requirements, to support your product development and market layout.