【Latin Name】:Betula platyphylla
【CAS 】: 473-98-3
【Part Used】: Bark
【Active Ingredients】: Betulin 【Specification】: Betulin Min 30%
Betulin Min 98%
【Appearance】: White Powder
【Test Method】: HPLC
【Molecular Formula】: C30H50O2
- Product Description
Birch Bark Betulin Powder: Premium Bioactive Triterpenoid for Nutraceuticals and Cosmeceuticals
In the science of contemporary formulations, natural bioactive substances have acquired much attention. The silvery outer bark of the birch tree (Betula platyphylla) in the virgin woods of Northeast China is the exclusive source of Birch Bark Betulin Powder, a premium pentacyclic triterpenoid. This bioactive material has multiple roles in cellular defense, metabolic support, and inflammatory regulation pathways. The powder is available in purity standards from 30% to 98%, meeting varied formulation needs for nutritional supplements and personal care applications, providing producers with a natural, research-supported component that fits with clean-label consumer needs.
Birch Bark Betulin Powder Specifications
|
Parameter |
Value |
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|
CAS Number |
473-98-3 |
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|
Latin Name |
Betula platyphylla |
||
|
Molecular Formula |
C₃₀H₅₀O₂ |
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|
Molecular Weight |
442.72 g/mol |
||
|
Part Used |
Bark (outer silvery layer only) |
||
|
Active Ingredient |
Betulin |
||
|
Specification |
30% min / 98% min |
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|
Appearance |
White crystalline powder |
||
|
Test Method |
HPLC |
||
|
Mesh Size |
80–200 mesh (customizable) |
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|
Test Item |
Standard Requirement |
Test Result |
Judgment |
|---|---|---|---|
|
Appearance |
White to off-white fine crystalline powder, no foreign impurities |
Off-white uniform fine powder |
Complies |
|
Identification |
HPLC retention time consistent with Betulin reference standard |
Positive identification |
Complies |
|
Betulin Content (HPLC) |
≥98.0% |
98.42% |
Complies |
|
Loss on Drying |
≤5.0% |
2.17% |
Complies |
|
Total Ash |
≤3.0% |
1.04% |
Complies |
|
Residue on Ignition |
≤0.2% |
0.08% |
Complies |
|
Single Unknown Impurity |
≤0.10% |
0.04% |
Complies |
|
Total Related Impurities |
≤1.0% |
0.35% |
Complies |
|
Particle Size |
80 mesh pass rate ≥95% |
99.2% |
Complies |
|
Solubility |
Slightly soluble in ethanol, insoluble in water |
Conforms |
Complies |
|
Residual Solvents |
Meet ICH Q3C limits |
Complies |
Complies |
|
Lead (Pb) |
≤10.0 ppm |
1.21 ppm |
Complies |
|
Arsenic (As) |
≤2.0 ppm |
0.43 ppm |
Complies |
|
Cadmium (Cd) |
≤1.0 ppm |
0.18 ppm |
Complies |
|
Mercury (Hg) |
≤0.1 ppm |
Not Detected |
Complies |
|
Total Aerobic Microbial Count |
≤1000 CFU/g |
140 CFU/g |
Complies |
|
Yeast & Mold Count |
≤100 CFU/g |
22 CFU/g |
Complies |
|
Escherichia coli |
Negative / g |
Negative |
Complies |
|
Salmonella spp. |
Negative / 25g |
Negative |
Complies |
|
Staphylococcus aureus |
Negative / g |
Negative |
Complies |
Why Choose Us
Shaanxi Rebecca Biotechnology Co., Ltd. is a vertically integrated manufacturer of plant derived bioactives.
- Our factory utilises state of the art extraction technology and adheres to strict quality norms.
- We provide complete traceability from the collecting of raw bark in the Greater Khingan forests to the delivery of the end product.
- The manufacturing line is equipped with high-temperature drying systems, ultra-fine grinding and macroporous resin purification machines, guaranteeing constant and high batch quality.
- Our R&D team is constantly working on optimising the extraction parameters for maximum betulin yield and removal of solvent residues.
- We are ISO9001, HALAL, KOSHER, cGMP, ISO22000, FSSC22000, HACCP Certified.
- All shipments meet EU EC396 and EU 2023/915 requirements.
- Every batch comes with complete support for third party testing with SGS, Eurofins and Intertek.

Source & Traceability
The raw materials are obtained only from wild birch forests of the Greater and Lesser Khingan mountain ranges and Inner Mongolia grasslands. Its cold temperate continental climate (long winters and intense summer sunlight) favours the accumulation of betulin in bark tissue. The manual collection focuses on mature trunks, while damaged, mouldy or inner bark layers are rejected.
It is grown wild, so there is no exposure to artificial fertilisers and pesticides. Each batch is tested for heavy metals, pesticide residues and mycotoxins. Each delivery is supported by full origin records and batch traceability files to provide supply chain transparency from forest to warehouse.

Solubility & Stability Profile
Solubility Characteristics:
Insoluble in cold water and pure water systems. Slightly soluble in hot ethanol, methanol, propylene glycol, and alkaline solutions. When formulating aqueous cosmetics or beverages, emulsifiers or co-solvents are essential for dispersion.
Stability Parameters:
· Thermal: Stable below 60°C; prolonged exposure above this threshold degrades triterpenoid structure.
· Light: Highly photosensitive—requires opaque packaging to prevent yellowing and activity loss.
· pH: Optimal stability in neutral to mildly acidic conditions (pH 5.0–7.0); strong alkaline environments compromise molecular integrity.
· Moisture: Slight hygroscopicity demands sealed, dry storage to prevent caking during transport.
· Shelf Life: 24 months under controlled conditions (cool, dry, light-protected).

Production Process
The production process of Birch Bark Betulin Powder starts by sifting the bark, which is washed with purified water and dried at low temperatures in an air dryer.
Bark fragments are obtained by closed system ethanol reflux below 55 °C to maintain the betulin integrity.
Solid residues are removed by multi-stage filtration.
Betulin is selectively adsorbed on macroporous resin columns to remove tannins and colours.
Food-grade ethanol is recovered by vacuum concentration under light-protected conditions.
Gradient cooling recrystallisation is a method of purification of crude extracts to higher levels.
Thermal decomposition is prevented by hoover drying.
Ultrafine pulverisation creates 80-200 mesh particles for capsules or cosmetic emulsions.
Blending in large batches guarantees uniformity of colour and purity.
Final packaging is in vacuum sealed aluminium bags with nitrogen in 25 kg fibre drums.
Each batch is fully tested physically, chemically and microbiologically before to distribution.

Applications & Benefits
Dietary Supplements:
Formulated into immune support capsules, antioxidant powders and metabolic conditioning mixtures. Betulin modulates inflammation pathways and helps in building resilience of cells, so it is a perfect ingredient for anti-aging and wellness products.
Cosmetics & Personal Care:
Commonly used in anti-aging serums, toners for sensitive skin, acne repair treatments, and body care lotions. The chemical stimulates keratin metabolism, decreases irritation, and improves the skin barrier function. It also acts as a natural preservative auxiliary in clean-label skincare systems.

Packaging & Delivery
Standard Packaging:
Inner layer: Nitrogen-filled, vacuum-sealed aluminum foil bag.
Outer layer: 25 kg food-grade fiber drum with tamper-evident seal.
Customization Options:
Flexible pack sizes (1kg, 5kg, 10kg, 25kg) to suit order volume. Private labelling, unique mesh sizes and dosage form creation (tablets, hard/soft capsules, liquid ready formulations) are offered. OEM/ODM services provide comprehensive product line development from idea to commercialisation.
Shipping Methods:
Air freight for urgent or small-volume orders (<100 kg).
Sea freight for bulk shipments (>500 kg) with temperature-controlled containers.
DDP (Delivered Duty Paid) terms available to major ports worldwide. Our logistics network ensures rapid, secure delivery with real-time tracking support.

Frequently Asked Questions
Q: How do you manage the temperature of extraction such that it does not oxidise?
A: All activities are carried out below 55 °C in light-shielded systems to preserve the triterpenoid structure and avoid loss of purity.
Q: Do you offer COA with HPLC data for every batch?
A: Sure. All shipments are accompanied with full COA and HPLC chromatographs. Third party testing sponsored by SGS, Eurofins or Intertek.
Q: Are there any long term price agreements?
A: Framework customers benefit from quarterly price locking and priority in production scheduling so they can plan for predictable costs and stable supply.
Q: Is the powder suitable for water-based formulations?
A: Emulsifiers or co-solvents are required for aqueous systems. We offer technical guidance for optimal dispersion in various matrices.
Q: What is the typical lead time for bulk orders?
A: Standard orders ship within 10–15 business days. Custom specifications may require 20–25 days depending on complexity.
Contact us
For technical specifications, custom formulations, or sample requests, contact our Birch Bark Betulin Powder’s team at information@sxrebecca.com. We deliver natural, research-backed ingredients that meet the highest industry standards.
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